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Published on: August 11, 2023
Is Spectral-Domain Optical Coherence Tomography Always Able to Detect the Anti-Vascular Endothelial Growth Factor
Luigi Borgia1, Chiara Del Noce2, Michele Iester2
1Casa di Cura Clinica Montallegro, Genoa, Italy.
Purpose:
To show the presence of an active neovascular membrane in age-related macular degeneration even if optical coherence tomography (OCT) does not detect intra- or subretinal edema.
Methods:
This is a retrospective case report. During the follow-up after the intravitreal injection, 3 patients showed no intraretinal or subretinal edema by OCT; however, there was a progressive reduction in their visual acuity; thus, a fluorangiography (FA) examination was performed.
Results:
In these 3 cases, FA showed an active neovascular network.
Conclusion:
OCT could show a real reduction in the edema, but it is not always able to detect neovessel presence. Intravitreal injection could improve the vessel permeability without care and delete the neovascular network.
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