Related Experiment Video
Updated: Mar 17, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
[Intraocular Inflammation: Autoimmune or Infectious?]
C Auw-Hädrich1, S Heinzelmann1, S Coupland2
1Klinik für Augenheilkunde, Universitätsklinikum Freiburg.
Abstract:
Presentation of 3 cases of intraocular inflammation: 1. 47-year old female patient with severe necrotising scleritis and uveitis with underlying granulomatous polyangiitis (formerly known as Wegener granulomatosis, in honour of the German pathologist Friedrich Wegener), known for 10 years. 2. 48-year old male patient with longstanding bilateral uveitis and granulomatous polyangiitis for 2 years. In the histopathological examination of the enucleation specimen, a retrolental tumour turned out to be a granuloma. 3. 57-year old male patient in status post renal transplantation with intraocular cellular infiltration suspicious for lymphoma, which surprisingly proved to be Toxoplasma gondii-associated uveitis. The clinical course and characteristic histological signs and therapeutic options are discussed.
Related Concept Videos
Glaucoma: Overview
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Myocarditis I: Introduction
Inflammatory Response I: Vascular and Cellular
Inflammation
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

