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Renal Angiomyolipoma: Mid- to Long-Term Results Following Embolization with Onyx
Narayanan Thulasidasan1, Srividhiya Sriskandakumar2, Shahzad Ilyas2
1Department of Interventional Radiology, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, SE1 7EH, UK. narayanant@doctors.net.uk.
Purpose:
Percutaneous transcatheter embolization is currently the preferred treatment for ruptured or enlarging renal angiomyolipoma (AML), although the optimum choice of embolic material has not yet been established. We present mid- to long-term outcomes following embolization of AMLs with Onyx.
Materials And Methods:
Ten AMLs in seven patients (including two with tuberous sclerosis) were embolized with Onyx. Patients were followed-up clinically, with tumour size and renal function measured pre- and post-procedure.
Results:
Mean pre-treatment AML size was 63.4 mm (range 42-100). Mean clinical follow-up was 431.4 days (range 153-986) and imaging follow-up 284.2 days (range 30-741). There was no haemorrhage from treated lesions within the follow-up period. Of patients who had cross-sectional imaging pre- and post-procedure, mean decrease in AML size of 22 mm was seen after Onyx embolization (p = 0.0058, 95 % CI 9.13-34.87). No significant difference between serum creatinine was seen pre- and post-procedure (p = 0.54, 95 % CI 8.63-4.85).
Conclusions:
Onyx embolization of renal AMLs is effective in the medium to long term, with theoretical benefits in safety and durability of result.
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