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Updated: Mar 17, 2026

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Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
Published on: February 9, 2024
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Sensitive SERS detection of miRNA via enzyme-free DNA machine signal amplification
Xiaoxiao Li1, Sujuan Ye1, Xiliang Luo1
1Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China. xiliangluo@qust.edu.cn yesujuan@126.com.
Abstract:
In this work, an enzyme-free signal amplified detection platform is described for miRNA detection with a DNA fueled molecular machine. Coupling SERS technology with multiple amplification modes, this flexible biosensing system exhibits high sensitivity and specificity.

