Related Experiment Video
Updated: Mar 17, 2026

06:06
Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
3.3K
Low-level laser therapy and invisible removal aligners.
G Caccianiga1, C Crestale2, M Cozzani2
1School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Journal of Biological Regulators and Homeostatic Agents
|July 30, 2016
Summary
Low Level Laser Therapy (LLLT) accelerates orthodontic tooth movement with invisible aligners, reducing daily wear time. This innovative approach enhances treatment efficiency and patient comfort.
Area of Science:
- Orthodontics
- Biotechnology
- Dental Medicine
Background:
- Orthodontic treatments often involve prolonged wear times for aligners.
- Low Level Laser Therapy (LLLT) has shown potential in stimulating bone turnover and accelerating tooth movement.
- Integrating LLLT with clear aligner therapy could offer a more efficient and comfortable treatment experience.
Purpose of the Study:
- To evaluate the influence of LLLT on orthodontic tooth movement using invisible removable aligners.
- To compare treatment outcomes between patients receiving LLLT and a control group.
- To assess the potential of LLLT to reduce aligner wear time.
Main Methods:
- A sample of 21 subjects was divided into a laser group (10 patients) and a control group (11 patients).
- All subjects wore aligners for 12 hours daily.
- The laser group received external bio-stimulation with LLLT every second week.
Main Results:
- The laser group successfully completed treatment, whereas the control group did not complete treatment at the 3rd-5th aligner stage.
- LLLT combined with aligners achieved the same tooth movement in 12 hours as traditional protocols requiring 22 hours of wear.
- Laser treatment demonstrated superior outcomes compared to treatment without laser.
Conclusions:
- LLLT significantly enhances the efficacy of invisible removable aligner treatment.
- Combining LLLT with aligners allows for reduced daily wear time, improving patient compliance and comfort.
- LLLT presents a promising adjunctive therapy for accelerating orthodontic tooth movement with clear aligners.

