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Related Experiment Video

Updated: Mar 17, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
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Harlequin Ichthyosis: A Surgical Perspective.

Mitchell A Pet1, Deepti Gupta2, Raymond W Tse3

  • 1Plastic and Reconstructive Surgery, Seattle Children's Hospital, Seattle, Washington. mitchpet@uw.edu.

Pediatric Dermatology
|July 30, 2016
PubMed
Summary
This summary is machine-generated.

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Surgical release of constrictive plaques in harlequin ichthyosis can prevent tissue injury. This case report details the perioperative and intraoperative considerations for this rare but critical intervention.

Area of Science:

  • Dermatology
  • Surgical Oncology
  • Pediatric Surgery

Background:

  • Harlequin ichthyosis is a severe genetic skin disorder.
  • Limb constriction in harlequin ichthyosis can lead to necrosis and auto-amputation.
  • Surgical release of constrictive plaques is a potential intervention.

Observation:

  • A case of harlequin ichthyosis requiring surgical intervention for limb constriction is presented.
  • The patient experienced tissue injury due to constrictive plaques.
  • Early surgical consultation was deemed crucial.

Findings:

  • The report details the risks, indications, and timing of surgical intervention.
  • Perioperative and intraoperative considerations for surgical release were analyzed.

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  • The surgical procedure itself is described in detail.
  • Implications:

    • Highlights the importance of multidisciplinary care in managing harlequin ichthyosis.
    • Provides a guide for surgical management of limb constriction in this condition.
    • Emphasizes the potential for surgical intervention to prevent severe complications like auto-amputation.