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EQ-5D in Central and Eastern Europe: 2000-2015.
Fanni Rencz1,2, László Gulácsi3, Michael Drummond4
1Department of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary.
Summary
This systematic review found increasing use of the EQ-5D instrument across Central and Eastern Europe, highlighting the need for improved methodological quality and standardized value sets for health technology assessment.
Area of Science:
- Health Economics
- Outcomes Research
- Public Health
Background:
- Cost-effectiveness analysis, including cost per quality-adjusted life year (QALY) data, is crucial for reimbursement decisions in Central and Eastern European (CEE) countries.
- The EQ-5D (EuroQol 5 Dimensions) is the predominant instrument for generating utility values in the CEE region.
Observation:
- A systematic review identified 143 studies from eight CEE countries (Austria, Bulgaria, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia) published up to July 2015.
- Cardiovascular, neurologic, musculoskeletal, and endocrine/nutritional/metabolic diseases were the most frequently studied clinical areas.
- While EQ VAS and EQ-5D index scores were reported in most studies, a significant proportion did not specify the applied tariff, impacting comparability.
Findings:
- Hungary, Poland, and Slovenia have established population norms for EQ-5D.
- National EQ-5D value sets are available for Poland and Slovenia.
- The number of EQ-5D studies correlates with the expansion of health technology assessment (HTA) activities in the region.
Implications:
- There is a growing adoption of EQ-5D across CEE, reflecting increased HTA implementation.
- Methodological rigor and reporting quality in EQ-5D studies require enhancement for reliable health economic evaluations.
- To ensure comparability in the absence of national value sets, the UK tariff is recommended, and regional collaboration among CEE countries should be fostered.
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