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Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

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Large plaques on a baby boy.

Jonathan Karnes¹, Carrie Griffin²

¹Dermatology Services, Maine-Dartmouth Family Medicine Residency, Augusta, ME, USA.

The Journal of Family Practice

|July 31, 2016

Summary

A newborn presented with unusual brown and black plaques despite normal prenatal tests, delivery, Apgar scores, and neurologic examination. This case highlights a rare presentation requiring further investigation into the cause of these cutaneous findings.

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Area of Science:

Neonatal Dermatology
Pediatric Pathology

Background:

Normal prenatal laboratory results and delivery are crucial indicators of newborn health.
Apgar scores and neurologic examinations are standard assessments for infant well-being immediately after birth.

Observation:

A newborn exhibited extensive brown and black plaques covering the skin.
The infant's physical examination revealed no other apparent abnormalities.

Findings:

Despite a normal prenatal workup, delivery, and initial neonatal assessments, the infant developed significant cutaneous lesions.
The etiology of the brown and black plaques remains undetermined from the initial presentation.

Implications:

This case underscores the importance of thorough dermatological evaluation in newborns, even with seemingly normal initial health assessments.
Further investigation is warranted to identify the underlying cause of these rare neonatal skin findings and guide appropriate management.