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Published on: June 16, 2022
Galactose-decorated light-responsive hydrogelator precursors for selectively killing cancer cells
Wei Ji1, Guofeng Liu1, Fang Wang1
1State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240, Shanghai, China. clfeng@sjtu.edu.cn.
Abstract:
A multi-functional gelator precursor with high photosensitivity is rationally designed, which can not only selectively target hepatocellular carcinoma (HCC) cells, but also form intracellular self-assembly triggered by light and subsequently inducing cell death. The study develops a methodology to design biological targets of supramolecular self-assembly under external stimuli for cancer research.
