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Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
Published on: May 10, 2018
Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion
Tsubasa Omi1, Keisen Riku1, Motoyuki Fukumoto1
1Department of Psychiatry, Osaka General Medical Center, 3-1-56 Bandai-higashi, Sumiyoshi, Osaka 5588558, Japan.
Abstract:
We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secretion. This report could help elucidate the relationship between atypical antipsychotics and glucose metabolism.
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