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Nuclear myosin I regulates cell membrane tension

Tomáš Venit1,2, Alžběta Kalendová1, Martin Petr1

  • 1Department of Biology of the Cell Nucleus, Institute of Molecular Genetics, AS CR, v.v.i., Videnska 1083, 142 20 Prague, Czech Republic.

Scientific Reports
|August 3, 2016
PubMed
Summary

Nuclear myosin 1 (NM1) regulates plasma membrane tension by linking the membrane to the cytoskeleton. NM1 deletion increases membrane elasticity and cell resistance to swelling, while overexpression reduces cell survival.

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