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Thirty-Year Trends in Mortality from Cerebrovascular Diseases in Korea
Seung Won Lee1, Hyeon Chang Kim2, Hye Sun Lee3
1Department of Public Health, Yonsei University Graduate School, Seoul, Korea.; Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul, Korea.
Insights
Cerebrovascular disease mortality significantly declined in Korea over 30 years. Despite this progress, cerebrovascular diseases remain a substantial health burden due to prevalent risk factors.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Cerebrovascular disease is a major cause of death and disability in Korea.
- Understanding mortality trends is crucial for public health interventions.
Purpose of the Study:
- To analyze cerebrovascular disease mortality trends in Korea over a 30-year period (1983-2012).
- To identify changes in mortality patterns for cerebrovascular disease, hemorrhagic stroke, and cerebral infarction.
Main Methods:
- Utilized national Cause of Death Statistics for mortality data.
- Calculated crude and age-adjusted mortality rates for men and women.
- Employed penalized B-spline methods to analyze 30-year mortality trends.
Main Results:
- Overall cerebrovascular disease mortality markedly declined (78% in men, 68% in women).
- Age-adjusted hemorrhagic stroke mortality peaked in 1994 and declined significantly thereafter.
- Cerebral infarction mortality increased until the early 2000s before rapidly decreasing.
Conclusions:
- Cerebrovascular disease mortality has decreased substantially in Korea but remains a public health concern.
- High prevalence of cardiovascular risk factors continues to contribute to the disease burden.
Background And Objectives:
Cerebrovascular disease is a leading cause of mortality and morbidity in Korea. Understanding of cerebrovascular disease mortality trends is important to reduce the health burden from cerebrovascular diseases. We examined the changing pattern of mortality related to cerebrovascular disease in Korea over 30 years from 1983 to 2012.
Subjects And Methods:
Numbers of deaths from cerebrovascular disease, hemorrhagic stroke, and cerebral infarction were obtained from the national Cause of Death Statistics. Crude and age-adjusted mortality rates were calculated for men and women for each year. Penalized B-spline methods, which reduce bias and variability in curve fitting, were used to identify the trends of 30-year mortality and identify the year of highest mortality.
Results:
During the 30 years, cerebrovascular disease mortality has markedly declined. The age-adjusted cerebrovascular disease mortality rate has decreased by 78% in men and by 68% in women. In the case of hemorrhagic stroke, crude mortality peaked in 2001 but age-adjusted mortality peaked in 1994. Between 1994 and 2012, age-adjusted mortality from hemorrhagic stroke has decreased by 68% in men and 59% in women. In the case of cerebral infarction, crude and age-adjusted mortality rates steeply increased until 2004 and 2003, respectively, and both rates decreased rapidly thereafter.
Conclusion:
Cerebrovascular disease mortality rate has significantly decreased over the last 30 years in Korea, but remains a health burden. The prevalence of major cardiovascular risk factors are still highly prevalent in Korea.
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