Bupropion improved apathy in behavioral variant frontotemporal dementia: a case report
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Published on: July 16, 2014
Chia-Pei Lin1, Chih-Pang Chu2, Hsing-Cheng Liu3,4
1a Department of Psychiatry , Taipei Medical University-Shuang Ho Hospital , New Taipei City , R.O.C.
Abstract:
Apathy is a common neurobehavioral sign in cases of behavioral variant frontotemporal dementia. However, there is still no established sustained effective treatment. We present the case of a 65-year-old man with behavioral variant frontotemporal dementia who suffered from severe apathy, but his apathy improved after a 10-month period of bupropion treatment. His single photon emission computed tomography report also showed slight improvement. To the best of our knowledge, such a case with imaging evidence has never been reported. Further studies to correlate the effects of bupropion on apathy in behavioral variant frontotemporal dementia patients are clearly needed.
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