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Related Experiment Video

Updated: Mar 16, 2026

Novel Assay for Cold Nociception in Drosophila Larvae

Novel Assay for Cold Nociception in Drosophila Larvae

Published on: April 3, 2017

[A girl with a cold foot].

E V Rouwet¹, S Ten Raa, H J M Verhagen

¹Erasmus MC, afd. Heelkunde, Rotterdam.

Nederlands Tijdschrift Voor Geneeskunde

|August 4, 2016

Summary

A 14-year-old girl experienced sudden limb ischemia due to popliteal artery entrapment syndrome and thromboembolism. Surgical intervention successfully restored blood flow and function, resolving the critical limb ischemia.

Area of Science:

Vascular Surgery
Pediatric Cardiology
Orthopedic Surgery

Background:

Popliteal artery entrapment syndrome (PAES) is a rare condition causing lower limb ischemia, often presenting in young athletes.
Thromboembolic events can complicate PAES, leading to acute limb ischemia.
Early diagnosis and intervention are crucial for limb salvage.

Observation:

A 14-year-old female presented with acute, painful, pale, and cold left foot with absent pedal pulses.
Neurological deficits including sensory and motor loss were noted in the affected limb.
Computed tomography (CT) angiography identified thromboembolic occlusion of crural arteries and entrapment of the popliteal artery by the gastrocnemius muscle.

Findings:

The patient underwent emergency thromboembolectomy to remove arterial clots.

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Popliteal artery patch angioplasty was performed to address the entrapment.

Release of the gastrocnemius muscle relieved the extrinsic compression on the popliteal artery.

Implications:

Successful surgical management of PAES with acute limb ischemia can lead to complete functional recovery.
This case highlights the importance of considering PAES in young patients with acute limb ischemia.
Multidisciplinary management involving vascular and orthopedic surgery is key for optimal outcomes in complex PAES cases.