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Physical Activity Level and Colorectal Cancer Mortality
Yejin Mok1, Christina Jeon1, Gyu Jang Lee2
11 Yonsei University, Seoul, Republic of Korea.
Asia-Pacific Journal of Public Health
|August 4, 2016
Summary
Regular physical activity, particularly higher intensity, may lower colon cancer mortality in men. This study examined physical activity and cancer death risk in a large Korean cohort.
Area of Science:
- Epidemiology
- Oncology
- Preventive Medicine
Background:
- Colorectal cancer (CRC) risk is reduced by physical activity.
- The specific impact of physical activity on colon versus rectum cancer mortality is not well-defined.
Purpose of the Study:
- To investigate the association between physical activity levels (length, frequency, intensity) and mortality from colon and rectum cancer.
- To differentiate the effects of physical activity on colon and rectum cancer mortality.
Main Methods:
- A large prospective cohort study of 226,089 Korean individuals.
- Cox proportional hazards models were used to assess associations between physical activity and cancer mortality.
Main Results:
- Regular physical activity was associated with a lower risk of colon cancer mortality in men, but not women.
- High-intensity physical activity showed a borderline significant reduction in colon cancer mortality for men.
- These associations were consistent across subgroups with specific health profiles (e.g., younger age, lower BMI, no cardiovascular disease).
Conclusions:
- Increased physical activity, in terms of length and intensity, was linked to decreased colon cancer mortality in men.
- Physical activity did not show a significant association with rectum cancer mortality in this cohort.
- Regular physical activity may improve survival outcomes for colon cancer patients.
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