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B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

Dara K Mohammad1,2, Raja H Ali3, Janne J Turunen1

  • 1Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska Hospital Huddinge, SE-141 86 Huddinge-Stockholm, Sweden.

Plos One
|August 4, 2016
PubMed
Summary

Researchers identified novel protein phosphorylation events regulated by Protein kinase B (AKT) and mTORC1/2 signaling following B cell receptor activation. This revealed conserved protein targets involved in gene regulation and RNA processing.

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