Related Experiment Video
Updated: Mar 16, 2026

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
Published on: June 7, 2024
[Two compartment model of body composition and abdominal fat area in postmenopausal women - pilot study]
Magdalena Milewska1, Milena Mioduszewska2, Mariusz Pańczyk3
1Zakład Żywienia Człowieka, Wydział Nauki o Zdrowiu, Warszawski Uniwersytet Medyczny, Warszawa, ul. Erazma Ciołka 27 01-445 Warszawa tel. (+ 48 22) 836 09 71
Introduction:
Both menopausal period and aging have influence on body composition, increase of total body fat and visceral fat in particular. We should be aware that changes in body composition, mainly fat translocation to abdominal region, can occur without significant changes in body weight. Therefore quantitative abdominal fat assessment should be our aim.
The Aim:
Body composition analysis based on two compartment model and abdominal fat area assessment in cross section.
Material And Methods:
Subjects in postmenopausal period (41 women) were recruited for this study and divided into 2 groups: group 1 - women aged 45-56 years and group 2 - women aged 57-79 years. Body composition analysis and abdominal fat area assessment were conducted by using bioelectrical impedance method with BioScan 920 (Maltron int.) accordingly with standardized procedure.
Results:
Women in early postmenopausal stage (Group 1) had statistically significant lower total body fat percentage in comparison with women in late postmenopausal period (Group 2) (41.09 ± 7.72% vs. 50.7 ± 9.88%, p=0.0021). Also women in group 1 were characterized by significant lower visceral fat area (VAT) as well as subcutaneous fat area (SAT) in comparison with group 2 (respectively VAT 119.25 ± 30.09 cm2 vs. 199.36 ± 87.38 cm2, p=0.0011; SAT 175.19 ±57.67 cm2 vs. 223.4±74.29 cm2, p=0.0336). According to VAT criteria (>120 cm2), 44% of women in group 1 and 80% in group 2 had excess of visceral fat.
Conclusions:
Both total body fat and intra-abdominal fat increased with age, independently of weight changes.
Related Concept Videos
Compartment Models: Two-Compartment Model
Two-Compartment Open Model: Overview
The...
Multicompartment Models: Overview
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
Three-Compartment Open Model
Cholesterol: Significance and Regulation
Considering cholesterol and...
Model Approaches for Pharmacokinetic Data: Compartment Models
Two primary types of compartment models are recognized: mammillary and catenary. The more...

