Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic Algorithm for Axial Involvement in Psoriatic Arthritis.

Doklady. Biochemistry and biophysics·2026
Same author

[Amyloidogenesis and neurotrophic dysfunction in age-related macular degeneration in correlation with Alzheimer's disease].

Arkhiv patologii·2025
Same author

Evaluation of the Antitumor Effect of High-Energy Protons, Helium Ions, and Carbon during Irradiation of Ehrlich Adenocarcinoma Ascites Cells Ex Vivo.

Doklady. Biochemistry and biophysics·2025
Same author

Comparative Characteristics of Axial Spondyloarthritis and Psoriatic Arthritis with Axial Involvement.

Doklady. Biochemistry and biophysics·2025
Same author

Studying concatenation of the Cas9-cleaved transgenes using barcodes.

Vavilovskii zhurnal genetiki i selektsii·2025
Same author

Management of radiation-induced proctitis using submucosal endoscopic injections of autologous adipose-derived stromal vascular fraction: a case report.

Stem cell research & therapy·2024

Related Experiment Video

Updated: Mar 16, 2026

A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure
09:06

A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure

Published on: October 24, 2018

11.3K

[CHARACTERISTICS OF THE RETINA IN CHRONIC STRESS IN LABORATORY RATS OF DIFFERENT AGE GROUPS].

A A Nesterova, V V Yermilov, I N Tiurenkov

    Morfologiia (Saint Petersburg, Russia)
    |August 5, 2016
    PubMed
    Summary

    Chronic stress, including pulsed light and loud sound, damages rat retinas. Cell numbers and layer structure significantly decrease in both young and old stressed rats compared to controls.

    More Related Videos

    Author Spotlight: Establishing a Rodent Model for Investigating Depression Factors in Traditional Mongolian Medicine
    05:56

    Author Spotlight: Establishing a Rodent Model for Investigating Depression Factors in Traditional Mongolian Medicine

    Published on: October 27, 2023

    1.9K
    Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
    08:29

    Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

    Published on: October 10, 2012

    16.9K

    Related Experiment Videos

    Last Updated: Mar 16, 2026

    A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure
    09:06

    A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure

    Published on: October 24, 2018

    11.3K
    Author Spotlight: Establishing a Rodent Model for Investigating Depression Factors in Traditional Mongolian Medicine
    05:56

    Author Spotlight: Establishing a Rodent Model for Investigating Depression Factors in Traditional Mongolian Medicine

    Published on: October 27, 2023

    1.9K
    Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
    08:29

    Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

    Published on: October 10, 2012

    16.9K

    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Toxicology

    Context:

    • The retina is a crucial component of the visual system, susceptible to environmental stressors.
    • Understanding the impact of chronic stress on retinal structure is vital for visual health research.
    • Albino laboratory male rats (12 and 24 months old) were used to model stress-induced retinal changes.

    Purpose:

    • To investigate the morphological changes in the retina of rats subjected to chronic combined stress.
    • To compare the effects of stress on retinal layers and cell density across different age groups.
    • To establish a baseline for stress-induced retinal damage in a controlled experimental setting.

    Summary:

    • Rats exposed to chronic combined stress (pulsed light, loud sound, swinging, immobility) for 7 days showed significant retinal alterations.
    • Histological analysis revealed a decrease in cell number and disorganization of retinal layers, particularly in photoreceptor and ganglion cell layers.
    • Morphometric analysis confirmed reduced layer thickness and cell numerical density in stressed rats compared to age-matched controls.

    Impact:

    • This study highlights the detrimental effects of chronic stress on retinal integrity and neuronal populations.
    • Findings suggest that stress can compromise visual function by damaging key retinal structures.
    • Provides evidence for the need to consider environmental stressors in the context of eye health and disease prevention.