Related Experiment Video
Updated: Mar 16, 2026
Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
Functional Status Score for the ICU: An International Clinimetric Analysis of Validity, Responsiveness, and Minimal
Minxuan Huang1, Kitty S Chan, Jennifer M Zanni
11Outcome After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University School of Medicine, Baltimore, MD.2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.3Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.4Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD.5Department of Physiotherapy, School of Health Sciences, University of Melbourne, Melbourne, VIC, Australia.6Department of Physical Therapy, Universidade Catolica de Brasilia, Brasilia, Brazil.7Department of Physical Therapy, Hospital Santa Luzia, Brasilia, Brazil.8Department of Research and Education, D'OR Institute, Brasilia, Brazil.9Health Sciences Program, Escola Superior de Ciencias da Saude, Brasilia, Brazil.10Department of Physical Therapy, Hospital de Base do Distrito Federal, Brasilia, Brazil.11School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada.
Objectives:
To evaluate the internal consistency, validity, responsiveness, and minimal important difference of the Functional Status Score for the ICU, a physical function measure designed for the ICU.
Design:
Clinimetric analysis.
Settings:
Five international datasets from the United States, Australia, and Brazil.
Patients:
Eight hundred nineteen ICU patients.
Intervention:
None.
Measurements And Main Results:
Clinimetric analyses were initially conducted separately for each data source and time point to examine generalizability of findings, with pooled analyses performed thereafter to increase power of analyses. The Functional Status Score for the ICU demonstrated good to excellent internal consistency. There was good convergent and discriminant validity, with significant and positive correlations (r = 0.30-0.95) between Functional Status Score for the ICU and other physical function measures, and generally weaker correlations with nonphysical measures (|r| = 0.01-0.70). Known group validity was demonstrated by significantly higher Functional Status Score for the ICU scores among patients without ICU-acquired weakness (Medical Research Council sum score, ≥ 48 vs < 48) and with hospital discharge to home (vs healthcare facility). Functional Status Score for the ICU at ICU discharge predicted post-ICU hospital length of stay and discharge location. Responsiveness was supported via increased Functional Status Score for the ICU scores with improvements in muscle strength. Distribution-based methods indicated a minimal important difference of 2.0-5.0.
Conclusions:
The Functional Status Score for the ICU has good internal consistency and is a valid and responsive measure of physical function for ICU patients. The estimated minimal important difference can be used in sample size calculations and in interpreting studies comparing the physical function of groups of ICU patients.
More Related Videos
11:05SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
Published on: February 6, 2021
10:38Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
