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Updated: Mar 16, 2026

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
A novel methodology to characterize interfacility transfer strategies in a trauma transfer network
David Gomez1, Barbara Haas, Kristian Larsen
1From the Division of General Surgery, Department of Surgery (D.G., H.T., A.B.N.), University of Toronto, Ontario, Canada; Sunnybrook Research Institute (D.G., B.H., A.A., H.T., G.R., A.B.N.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Interdepartmental Division of Critical Care (B.H., A.S.A., J.M.S., J.R.), University of Toronto, Ontario, Canada; Child Health Evaluative Sciences (K.L.), The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Geography and Planning (K.L), University of Toronto, Ontario, Canada; Ornge Transport Medicine (R.D.M., H.T.), Mississauga, Ontario, Canada; Division of Emergency Medicine, Department of Medicine (R.D.M.), University of Toronto, Ontario, Canada; Toronto Western Research Institute (J.M.S.), Toronto Western Hospital, Toronto, Ontario, Canada; and Department of Internal Medicine (T.J.I.), University of Michigan Medical School, Ann Arbor, Michigan.
Background:
More than half of severely injured patients are initially transported from the scene of injury to nontrauma centers (NTCs), with many requiring subsequent transfer to trauma center (TC) care. Definitive care in the setting of severe injury is time sensitive. However, transferring severely injured patients from an NTC is a complex process often fraught with delays. Selection of the receiving TC and the mode of interfacility transport both strongly influence total transfer time and are highly amenable to quality improvement initiatives.
Methods:
We analyzed transfer strategies, defined as the pairing of a destination and mode of transport (land vs. rotary wing vs. fixed wing), for severely injured adult patients. Existing transfer strategies at each NTC were derived from trauma registry data. Geographic Information Systems network analysis was used to identify the strategy that minimized transfer times the most as well as alternate strategies (+15 or +30 minutes) for each NTC. Transfer network efficiency was characterized based on optimality and stability.
Results:
We identified 7,702 severely injured adult patients transferred from 146 NTCs to 9 TCs. Nontrauma centers transferred severely injured patients to a median of 3 (interquartile range, 1-4) different TCs and utilized a median of 4 (interquartile range, 2-6) different transfer strategies. After allowing for the use of alternate transfer strategies, 73.1% of severely injured patients were transported using optimal/alternate strategies, and only 40.4% of NTCs transferred more than 90% of patients using an optimal/alternate transfer strategy. Three quarters (75.5%) of transfers occurred between NTCs and their most common receiving TC.
Conclusion:
More than a quarter of patients with severe traumatic injuries undergoing interfacility transport to a TC in Ontario are consistently transported using a nonoptimal combination of destination and mode of transport. Our novel analytic approach can be easily adapted to different system configurations and provides actionable data that can be provided to NTCs and other stakeholders.
Level Of Evidence:
Therapeutic study, level IV.

