Related Experiment Video

Updated: Mar 16, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.7K

Fungal prosthetic valve endocarditis with mycotic aneurysm: Case report

Mariana Brandão1, Jorge Almeida2, Rita Ferraz3

  • 1Escola de Ciências da Saúde, Universidade do Minho, Braga, Portugal.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|August 6, 2016
PubMed

Insights

This case study highlights a rare fungal prosthetic valve endocarditis caused by Candida albicans in a complex patient. Early antifungal treatment and homograft valve replacement led to a favorable outcome despite complications.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Mycology

Background:

  • Fungal prosthetic valve endocarditis (FPVE) is a severe complication of infective endocarditis with high mortality.
  • Candida albicans is the predominant pathogen in FPVE, a condition with increasing frequency.
  • Patients with complex cardiac histories, prior endocarditis, and renal failure are at increased risk.

Observation:

  • A 38-year-old woman with surgically corrected tetralogy of Fallot and prior infective endocarditis developed FPVE post-aortic and pulmonary valve replacement.
  • The patient required catheter-based hemodialysis due to acute renal failure.
  • A mycotic aneurysm developed, necessitating two vascular surgical interventions.

Findings:

  • Liposomal amphotericin B was administered pre-operatively, followed by homograft replacement of bioprostheses.
  • Successful management of the mycotic aneurysm and arterial ischemia was achieved.
  • The patient was discharged on suppressive oral fluconazole therapy for at least one year.

Implications:

  • This case underscores the importance of recognizing risk factors for fungal endocarditis.
  • It demonstrates the complexity of managing FPVE, including associated complications like mycotic aneurysms.
  • Aggressive antifungal therapy and surgical intervention, including homograft use, can lead to positive outcomes in challenging FPVE cases.
Keywords:
Aneurisma micóticoCandida albicansEndocardite de prótese valvularEndocardite fúngicaFungal endocarditisHomoenxertosHomograftsMycotic aneurysmProsthetic valve endocarditis

More Related Videos

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

688
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.4K

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
670
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
325
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
420
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
704
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
435
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
526