Related Experiment Video
Updated: Mar 16, 2026

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
Published on: October 10, 2025
NCCN Framework for Resource Stratification: A Framework for Providing and Improving Global Quality Oncology Care
Robert W Carlson1, Jillian L Scavone2, Wui-Jin Koh2
1From National Comprehensive Cancer Network, Fort Washington, Pennsylvania; Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania; Department of Medicine, Stanford University Medical Center, Stanford, California; and Fred Hutchinson Cancer Research Center, Seattle, Washington. From National Comprehensive Cancer Network, Fort Washington, Pennsylvania; Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania; Department of Medicine, Stanford University Medical Center, Stanford, California; and Fred Hutchinson Cancer Research Center, Seattle, Washington. From National Comprehensive Cancer Network, Fort Washington, Pennsylvania; Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania; Department of Medicine, Stanford University Medical Center, Stanford, California; and Fred Hutchinson Cancer Research Center, Seattle, Washington.
Cancer care disparities are significant globally, especially in low-income nations. The National Comprehensive Cancer Network (NCCN) developed a framework to adapt cancer guidelines for varying healthcare resource levels.
Area of Science:
- Oncology
- Global Health
- Health Equity
Background:
- Millions of new cancer cases and deaths occur annually, with a disproportionate burden in low- and middle-income countries.
- Significant disparities exist in healthcare resources, including health workers and financial support, between high-income and low-income regions.
- These resource disparities are particularly pronounced in cancer care, impacting treatment accessibility and outcomes.
Purpose of the Study:
- To introduce a framework for stratifying National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology (NCCN Guidelines).
- To address the challenge of providing optimal cancer care in settings with varying available resources.
- To adapt existing cancer guidelines for diverse healthcare environments.
Main Methods:
- Development of the NCCN Framework for Resource Stratification (NCCN Framework).
- Modification of a method previously developed by the Breast Health Global Initiative.
- Identification of four distinct resource environments: basic, core, enhanced, and NCCN Guidelines.
- Presentation of recommendations in a graphic format maintaining NCCN Guidelines context.
Main Results:
- The NCCN Framework stratifies guidelines based on resource availability.
- The framework ensures recommendations remain within the context of established NCCN Guidelines.
- A portion of the NCCN Cervical Cancer Guideline was used as an example to illustrate the methodology.
Conclusions:
- Resource-stratified guidelines are essential for optimizing cancer care globally.
- The NCCN Framework provides a structured approach to adapt cancer treatment guidelines.
- This methodology facilitates equitable cancer care delivery across diverse resource settings.
More Related Videos
07:13Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Related Concept Videos
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
International Nursing Organizations I
ICN member organizations work to advance the field of nursing and healthcare via policies, partnerships, lobbying, professional...
National Nursing Organizations II
The AACN emphasizes a healthy work environment through six standards to achieve an optimal patient outcome. The standards are appropriate staffing, meaningful recognition, collaboration, authentic leadership, effective communication, and decision-making. In addition, AACN provides certification programs, webinars, journals, and...
Standards of Care II
Standards of Care I
Nursing Interventions II: Selecting and Classifying the Nursing Interventions