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Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

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Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Related Experiment Video

Updated: Mar 16, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Imaging the Addicted Brain: Alcohol.

M Dupuy1, S Chanraud2

  • 1EA 4136-Handicap et Système Nerveux, Bordeaux University, Bordeaux, France; INCIA-Bordeaux University, UMR 5287 CNRS, Bordeaux, France.

International Review of Neurobiology
|August 10, 2016
PubMed
Summary
This summary is machine-generated.

Alcohol use disorder (AUD) causes brain changes, particularly in frontal systems. Magnetic resonance imaging (MRI) reveals a "disconnection syndrome" linked to impaired behavioral control in AUD patients.

Keywords:
Alcohol use disorderBrain activationFunctional connectivityMacrostructureMagnetic resonance imagingStructural connectivity

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Area of Science:

  • Neuroscience
  • Radiology
  • Public Health

Background:

  • Alcohol use disorder (AUD) is a significant public health concern with widespread negative impacts.
  • AUD affects personal life, relationships, and increases risks for conditions like brain injury.
  • Understanding AUD requires a multidisciplinary approach due to its complex nature.

Purpose of the Study:

  • To investigate brain alterations in individuals with AUD using advanced Magnetic Resonance Imaging (MRI) techniques.
  • To explore structural and functional changes in brain networks associated with AUD.
  • To synthesize findings from multiple MRI studies on AUD.

Main Methods:

  • Utilized various Magnetic Resonance Imaging (MRI) techniques to study brain structure and function.
  • Focused on studies employing multiple MRI methods for comprehensive analysis.
  • Analyzed data to identify consistent patterns of brain alterations in AUD.

Main Results:

  • MRI studies consistently indicate significant vulnerability in the frontal systems of the brain in individuals with AUD.
  • Evidence suggests a

Conclusions:

  • The findings support the existence of a