Related Experiment Video
Updated: Mar 16, 2026

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
Published on: July 26, 2019
Impact of pharmacist administration of influenza vaccines on uptake in Canada
Sarah A Buchan1, Laura C Rosella1, Michael Finkelstein1
1Epidemiology Division (Buchan, Rosella, Kwong), Dalla Lana School of Public Health, University of Toronto; Toronto Public Health (Finkelstein); Institute for Clinical Evaluative Sciences (Juurlink, Kwong), Toronto, Ont.; College of Pharmacy and Faculty of Medicine (Isenor), Dalhousie University, Halifax, NS; Faculty of Pharmaceutical Sciences (Marra) and Faculty of Medicine (Patel), University of British Columbia, Vancouver, BC; Cumming School of Medicine (Russell), University of Calgary, Calgary, Alta.; Public Health Ontario (Rosella, Quach, Kwong), Toronto, Ont.; School of Pharmacy (Waite), University of Waterloo, Waterloo, Ont.
Background:
Uptake of influenza vaccination in Canada remains suboptimal despite widespread public funding. To increase access, several provinces have implemented policies permitting pharmacists to administer influenza vaccines in community pharmacies. We examined the impact of such policies on the uptake of seasonal influenza vaccination in Canada.
Methods:
We pooled data from the 2007-2014 cycles of the Canadian Community Health Survey (n = 481 526). To determine the impact of influenza vaccine administration by pharmacists, we estimated the prevalence ratio for the association between the presence of a pharmacist policy and individual-level vaccine uptake using a modified Poisson regression model (dependent variable: vaccine uptake) with normalized weights while controlling for numerous health and sociodemographic factors.
Results:
Across all survey cycles combined, 28.8% of respondents reported receiving a seasonal influenza vaccine during the 12 months before survey participation. Introduction of a policy for pharmacist administration of influenza vaccine was associated with a modest increase in coverage (2.2%) and an individual's likelihood of uptake (adjusted prevalence ratio 1.05, 95% confidence interval 1.02-1.08).
Interpretation:
Uptake of influenza immunization was modestly increased in Canadian jurisdictions that allowed pharmacists to administer influenza vaccines.
Related Concept Videos
Vaccinations
Pharmacokinetics: Drug–Food and Drug–Viral Interactions
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Pharmaceutical Poisoning: Potential Scenarios
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Factors Affecting Drug Response: Overview

