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Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

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Multimodality Imaging of Neurodegenerative Processes: Part 2, Atypical Dementias.

Erica L Martin-Macintosh¹, Stephen M Broski¹, Geoffrey B Johnson¹

¹1 Department of Radiology, Division of Nuclear Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

AJR. American Journal of Roentgenology

|August 10, 2016

Summary

Multimodality imaging aids in diagnosing rare atypical neurodegenerative dementias. Understanding these advanced imaging patterns is crucial as their use increases.

Keywords:

brain dementia molecular imaging neurodegenerative

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Area of Science:

Neurology
Radiology
Medical Imaging

Background:

Part 1 of this series covered common dementia imaging.
Atypical neurodegenerative conditions require specialized diagnostic approaches.

Purpose of the Study:

To describe multimodality imaging's role in evaluating atypical neurodegenerative conditions.
To discuss Centers for Medicare & Medicaid Services coverage for dementia imaging.
To illustrate combining anatomic, metabolic, and amyloid imaging for atypical dementia.

Main Methods:

Review of current literature and imaging techniques.
Focus on integrating different imaging modalities.
Discussion of diagnostic criteria for rare dementias.

Main Results:

Multimodality imaging offers a comprehensive approach to atypical neurodegenerative dementias.
Anatomic, metabolic, and amyloid imaging provide complementary diagnostic information.
Understanding specific imaging patterns is key for accurate diagnosis.

Conclusions:

Familiarity with imaging appearances of atypical neurodegenerative disorders is increasingly important.
Despite rarity, the use of advanced imaging for neurodegenerative disorders is rising.