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Updated: Mar 16, 2026
Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
Published on: May 30, 2012
Of Mice and Snakes: A Tail of Oct4
Natalia A Shylo1, Scott D Weatherbee1
1Department of Genetics, Yale University, New Haven, CT 06520, USA.
Abstract:
The vertebrate axial skeleton comprises regions of specialized vertebrae, which vary in length between lineages. Aires et al. (2016) uncover a key role for Oct4 in determining trunk length in mice. Additionally, a heterochronic shift in Oct4 expression may underlie the extreme elongation of the trunk in snakes.
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