Isolated brain metastasis from a small renal mass

Area of Science:

• Oncology
• Nephrology
• Neurology

Background:

• Small renal masses are increasingly detected.
• Active surveillance is a recommended management strategy for select patients.
• Metastasis from small renal masses during observation is uncommon.

Observation:

• A 73-year-old man presented with tonic-clonic seizures.
• The seizures were caused by a brain metastasis.
• The metastasis originated from a small renal mass (3.5 cm).

Findings:

• This is the first reported case of brain metastasis from a small renal mass.
• The patient's brain metastasis was successfully treated with whole brain radiotherapy.
• The patient will undergo continued surveillance and consideration for systemic therapy upon progression.

Implications:

• This case expands the known metastatic potential of small renal masses.
• It underscores the importance of considering metastasis in patients with unexplained neurological symptoms.
• Further research may be needed to refine surveillance and treatment strategies for renal masses with metastatic potential.