Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Abnormal Proliferation

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...

Abnormal Proliferation

Abnormal Proliferation

Classification of Epithelial Tissues: Glandular Epithelium

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...

Vesicular Tubular Clusters

Vesicular Tubular Clusters

After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi.
With the help of motor proteins such...

External Female Genitals

External Female Genitals

The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hydrogen sulfide donor sodium hydrosulfide modulates ovarian steroidogenesis and follicular integrity in a DHEA-induced rat model of polycystic ovary syndrome.

Frontiers in endocrinology·2026

Same author

Reply to: Indication-dependent heterogeneity in the effect of double-suture cerclage: concerns over indication classification and a call for stratified analysis.

Archives of gynecology and obstetrics·2026

Same author

Does suture number matter in transvaginal cervical cerclage? A propensity score-weighted cohort study.

Archives of gynecology and obstetrics·2026

Same author

Multicystic Adenomatoid Pancreatic Hamartoma in a Child: Case Report.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·2025

Same author

Assessing the efficacy of a novel sperm-washing medium enriched with serotonin, L-carnitine, and coenzyme Q10: an observational cohort study.

Asian journal of andrology·2024

Same author

Rare diagnosis of an Epstein-Barr virus-positive extracavitary/solid variant of primary effusion lymphoma by duodenal endoscopic biopsy in a human immunodeficiency virus-seronegative and immunocompetent patient: A case report.

Indian journal of pathology & microbiology·2024

Search research articles

Related Experiment Video

Updated: Mar 16, 2026

Primary Culture of Human Vestibular Schwannomas

Primary Culture of Human Vestibular Schwannomas

Published on: July 20, 2014

Vulvar granular cell tumor.

Fatma Cavide Sonmez¹, Nadiye Koroglu², Beril Guler¹

¹Department of Pathology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

Indian Journal of Pathology & Microbiology

|August 12, 2016

Summary

Granular cell tumors (GCTs) are rare neoplasms, infrequently occurring in the vulva. This case highlights a benign GCT of the vulva, emphasizing complete surgical excision for treatment.

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

A Unified Methodological Framework for Vestibular Schwannoma Research

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

Related Experiment Videos

Last Updated: Mar 16, 2026

Primary Culture of Human Vestibular Schwannomas

Primary Culture of Human Vestibular Schwannomas

Published on: July 20, 2014

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

A Unified Methodological Framework for Vestibular Schwannoma Research

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

Area of Science:

Oncology
Dermatology
Gynecologic Oncology

Background:

Granular cell tumors (GCTs) are rare neoplasms, with approximately 50% arising in the head and neck, particularly the tongue.
While typically benign, GCTs can exhibit malignant behavior, and recurrence rates are influenced by surgical margin status.
The peak incidence for GCTs is observed in the fourth to sixth decades of life, presenting as slow-growing nodules.

Observation:

This report details a rare case of a benign Granular Cell Tumor (GCT) located in the vulva.
A 41-year-old female patient presented with a vulvar mass, which was diagnosed as a GCT via biopsy.

Findings:

The biopsy confirmed the presence of a benign Granular Cell Tumor of the vulva.
Complete surgical excision is the standard treatment for GCTs, with clear margins crucial for preventing recurrence.

Implications:

This case underscores the importance of considering GCTs in the differential diagnosis of vulvar masses, despite their rarity in this location.
Accurate diagnosis and complete surgical removal are essential for optimal patient outcomes and minimizing the risk of recurrence for vulvar GCTs.