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Neurological melioidosis presenting as intracranial abscess
Deepak Madi1, Santosh P V Rai2, K Vidyalakshmi3
1Department of Internal Medicine, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India.
Indian Journal of Pathology & Microbiology
|August 12, 2016
Summary
Melioidosis, a serious emerging infection caused by Burkholderia pseudomallei, can affect any organ. Central nervous system involvement is rare but should be considered in diabetics presenting with intracranial abscess or meningoencephalitis.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Melioidosis is an emerging infectious disease caused by Burkholderia pseudomallei.
- It presents with diverse clinical manifestations, affecting virtually any organ.
- Central nervous system (CNS) involvement is an uncommon but severe presentation.
Observation:
- This report details a rare case of CNS melioidosis originating from South India.
- The patient's presentation involved neurological symptoms, highlighting the varied disease spectrum.
- The increasing incidence of diabetes in the region correlates with diverse melioidosis presentations.
Findings:
- Central nervous system melioidosis, though rare, can manifest as intracranial abscess or meningoencephalitis.
- Burkholderia pseudomallei is the causative agent, posing a significant diagnostic challenge.
- Early recognition is crucial for effective management of this severe infection.
Implications:
- Melioidosis must be included in the differential diagnosis for patients with intracranial abscess or meningoencephalitis.
- Healthcare providers, especially in endemic areas with rising diabetes rates, should be vigilant.
- Increased awareness can lead to earlier diagnosis and improved patient outcomes for CNS melioidosis.
