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Related Experiment Video

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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
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[Not Available].

Marcia Carolina Siqueira-Paese1, Diana Borges Dock-Nascimento, José Eduardo De Aguilar-Nascimento

  • 1Intensive Care Unit. Santa Rosa Hospital. Cuiaba, Brazil. aguilar@terra.com.br.

Nutricion Hospitalaria
|August 12, 2016
PubMed
Summary

Critically ill patients often experience significant caloric and protein deficits, increasing hospital stay. A protein deficit over 20 g/day independently raises mortality risk in intensive care units (ICUs).

Area of Science:

  • Critical care medicine
  • Nutritional science
  • Clinical research

Background:

  • Adequate nutrition is crucial for critically ill patients.
  • Caloric and protein deficits are common in intensive care units (ICUs).
  • Understanding the impact of nutritional deficits on patient outcomes is essential.

Purpose of the Study:

  • To investigate the influence of caloric and protein deficits on mortality.
  • To determine the effect of nutritional deficits on length of hospital stay in critically ill patients.

Main Methods:

  • Prospective cohort study of 100 ICU patients.
  • Daily monitoring of caloric and protein intake for up to 30 days.
  • Categorization of deficits into critical (≥480 kcal/day or ≥20 g/day) and non-critical levels.
Keywords:
Critical care. Enteral nutrition. Parenteral nutrition. Energy deficit. Mortality.

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Main Results:

  • 33% mortality rate observed.
  • Patients received only 65.4% of caloric and 67.7% of protein needs.
  • Significant correlation between accumulated caloric/protein deficits and increased hospital stay (p < 0.001).
  • Critical caloric and protein deficits associated with higher mortality (p < 0.01).
  • Critical protein deficit independently linked to increased mortality (HR 0.25, p = 0.03).

Conclusions:

  • High incidence of caloric and protein deficits in ICUs.
  • Both deficits prolong hospital stay.
  • Protein deficit >20 g/day is an independent predictor of mortality in critical care.