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Updated: Mar 16, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Adverse Effects of Electroconvulsive Therapy.
Chittaranjan Andrade1, Shyam Sundar Arumugham2, Jagadisha Thirthalli2
1Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560 029, India.
Electroconvulsive therapy (ECT) effectively treats psychiatric disorders. This review covers common and serious adverse effects (AEs) of ECT, emphasizing prevention and management strategies to minimize risks.
Area of Science:
- Neuroscience
- Psychiatry
- Clinical Medicine
Background:
- Electroconvulsive therapy (ECT) is a vital treatment for major psychiatric disorders like depression.
- Understanding and managing adverse effects (AEs) is crucial for optimizing ECT patient care.
Purpose of the Study:
- To review the spectrum of adverse effects associated with electroconvulsive therapy.
- To outline strategies for the prevention and management of ECT-related AEs.
Main Methods:
- Literature review of adverse events in electroconvulsive therapy.
- Discussion of symptomatic and physiological management approaches.
Main Results:
- Common acute AEs include headache, nausea, myalgia, and confusion, typically managed symptomatically.
- Serious, uncommon AEs involve cardiovascular, pulmonary, and cerebrovascular systems, minimized by risk screening and monitoring.
- While most cognitive AEs are transient, persistent retrograde amnesia is a rare concern.
Conclusions:
- ECT is an effective psychiatric treatment with manageable adverse effects.
- Proactive risk factor screening, physiological monitoring, and technique modifications enhance ECT safety.
- Symptomatic treatment and advanced techniques effectively mitigate most adverse events, improving patient outcomes.
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