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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antimicrobial Stewardship for the Infection Control Practitioner
Jerod L Nagel1, Keith S Kaye2, Kerry L LaPlante3
1Department of Pharmacy Services, University of Michigan Health System, Ann Arbor, MI 48109, USA.
Abstract:
Antibiotic misuse is a serious patient safety concern and a national public health priority. Years of indiscriminant antibiotic use has promoted selection for antibiotic resistant bacteria and Clostridium difficile This crisis has led to clinicians being faced with managing untreatable infections, often in the most vulnerable patient populations. This review summarizes the goals of antimicrobial stewardship programs, the essential members needed to initiate a program, various antimicrobial stewardship strategies, the role of the infection control practitioner in stewardship, barriers to its implementation and maintenance, approaches to measure the impact of a program, and the steps needed to initiate a program.
Insights
Antimicrobial stewardship programs combat antibiotic resistance and Clostridium difficile infections. This review outlines program goals, essential members, strategies, and implementation steps to improve patient safety.
Area of Science:
- Public Health
- Infectious Diseases
- Patient Safety
Background:
- Antibiotic misuse is a significant patient safety issue and a national public health concern.
- Indiscriminate antibiotic use has led to the rise of antibiotic-resistant bacteria and Clostridium difficile infections.
- This resistance crisis challenges clinicians managing untreatable infections, particularly in vulnerable populations.
Purpose of the Study:
- To review the objectives of antimicrobial stewardship programs.
- To identify essential personnel for program initiation.
- To discuss various antimicrobial stewardship strategies and implementation barriers.
Main Methods:
- Literature review summarizing key aspects of antimicrobial stewardship.
- Analysis of essential components for program establishment and maintenance.
- Examination of strategies for measuring program impact.
Main Results:
- Detailed overview of antimicrobial stewardship program goals and necessary team members.
- Exploration of diverse stewardship strategies and the role of infection control practitioners.
- Identification of common barriers to implementation and maintenance, with suggested approaches.
Conclusions:
- Effective antimicrobial stewardship programs are crucial for combating antibiotic resistance.
- Successful implementation requires a multidisciplinary approach and strategic planning.
- Measuring program impact is essential for continuous improvement and patient safety.
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