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Microbe-microbe interactions trigger Mn(II)-oxidizing gene expression.

Jinsong Liang1,2, Yaohui Bai1, Yujie Men3

  • 1Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.

The ISME Journal
|August 13, 2016
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Summary
This summary is machine-generated.

Microbial interactions can activate manganese(II) oxidation. Co-culturing Arthrobacter and Sphingopyxis bacteria induced manganese oxidation via contact-dependent gene activation and stress response.

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Area of Science:

  • Geomicrobiology
  • Microbial Ecology

Background:

  • Manganese (Mn) is crucial in geochemical cycles, with microbial oxidation of Mn(II) to Mn oxides impacting global element cycles.
  • Microbe-microbe interactions are vital in biological processes, but their role in Mn(II) oxidation is largely unknown.

Purpose of the Study:

  • To investigate the effect of microbial interactions on Mn(II) oxidation.
  • To identify the mechanisms underlying Mn(II) oxidation in a co-culture system.

Main Methods:

  • Co-cultivation of Arthrobacter sp. and Sphingopyxis sp.
  • Purification and identification of Mn(II)-oxidizing protein.
  • Gene sequencing (boxA) and transcriptomic analysis (RNA-Seq).
  • Extracellular superoxide detection and flow cytometry.

Main Results:

  • Neither bacterium oxidized Mn(II) in isolation, but co-cultivation showed significant Mn(II)-oxidizing activity.
  • Contact-dependent interactions induced the expression of a bilirubin oxidase (boxA) in Arthrobacter.
  • boxA gene expression was activated by Sphingopyxis presence, linked to a stress response and superoxide production.

Conclusions:

  • Microbial interactions, specifically stress responses triggered by co-cultivation, can induce Mn(II) oxidation.
  • This study reveals a novel mechanism for Mn(II) oxidation mediated by inter-bacterial communication and physiological stress.