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Ventricular premature contraction associated with mitral valve prolapse
Hong-TaoYuan1, Mei Yang2, Li Zhong2
1Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
International Journal of Cardiology
|August 15, 2016
Summary
Mitral valve prolapse (MVP) patients with frequent premature ventricular contractions (PVCs) show similar PVC frequency and treatment outcomes compared to those without MVP. Survival rates were also comparable between groups.
Area of Science:
- Cardiology
- Electrophysiology
- Valvular Heart Disease
Background:
- Limited understanding of premature ventricular contractions (PVCs) in patients with mitral valve prolapse (MVP).
- Comparison of PVC characteristics and treatment outcomes between MVP and non-MVP patients is needed.
Purpose of the Study:
- To compare PVC profiles and treatment outcomes in patients with and without MVP.
- To evaluate the impact of MVP on the efficacy of catheter ablation and medical therapy for PVCs.
Main Methods:
- Retrospective analysis of patients with documented PVCs from 2001-2012.
- Division into MVP (n=112) and non-MVP (n=952) groups for comparison.
- Analysis of PVC origin, therapy response, and survival rates.
Main Results:
- Similar PVC frequency between MVP and non-MVP groups.
- Higher prevalence of PVCs originating from papillary muscles and fascicles in MVP patients, potentially complicating ablation.
- Comparable response rates to catheter ablation and medical therapy.
- Identical survival rates between the two groups.
Conclusions:
- Patients with significant PVC burden and MVP have similar PVC frequency, treatment success rates, and survival compared to non-MVP patients.
- MVP is associated with PVCs originating from specific cardiac structures, posing challenges for ablation but not affecting overall outcomes.
Keywords:
Antiarrhythmic drugMitral valve prolapsePremature ventricular contractionRadiofrequency catheter ablationMore Related Videos
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