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Selective Plasma Exchange for Critically Ill Patients Accompanied With Thrombocytopenia
Hajime Nakae1, Hirokazu Fukuda2, Manabu Okuyama1
1Department of Emergency and Critical Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.
Abstract:
Selective plasma exchange is a blood purification therapy in which simple plasma exchange is performed using a selective membrane plasma separator (pore size of 0.03 µm). Seven critically ill patients accompanied with thrombocytopenia were treated with selective plasma exchange using fresh frozen plasma. The total bilirubin levels and prothrombin time international normalized ratios decreased significantly after treatment. The total protein, albumin, and fibrinogen levels increased significantly after treatment. Selective plasma exchange may be a useful blood purification therapy for removing causal substances and retaining coagulation factors in patients accompanied with thrombocytopenia.
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