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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
Obesity Cardiomyopathy: Pathophysiologic Factors and Nosologic Reevaluation
Samit Bhatheja1, Hemang B Panchal1, Hector Ventura2
1Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee.
Abstract:
Cardiovascular disease in populations with obesity is a major concern because of its epidemic proportion. Obesity leads to the development of cardiomyopathy directly via inflammatory mediators and indirectly by obesity-induced hypertension, diabetes and coronary artery diseases. The aim of this review article is to re-visit the available knowledge and the evidence on pathophysiologic mechanisms of obesity-related cardiomyopathy and to propose its placement into a specific category of myocardial disease.
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