Related Experiment Video
Updated: Mar 16, 2026
05:39
Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery
Published on: June 23, 2023
2.4K
Diclofenac rectal suppository: an effective modality for perineal pain
Shabnam Naz1, Naila Yousuf Memon1, Asma Sattar1
1Shaheed Mohtarma Benazir Bhutto Medical University Larkana, Sindh, Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|August 16, 2016
Summary
A single dose of diclofenac rectal suppository effectively reduced postpartum perineal pain in women. This non-steroidal anti-inflammatory drug (NSAID) proved simple and highly effective for pain management after childbirth.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
- Pain Management
Background:
- Postpartum perineal pain is a common complication following vaginal delivery.
- Effective and simple pain relief strategies are crucial for maternal well-being.
- Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used for pain management.
Purpose of the Study:
- To evaluate the frequency of perineal pain after childbirth.
- To assess the efficacy of a single dose of diclofenac rectal suppository in managing postpartum perineal pain.
Main Methods:
- A cross-sectional study involving 169 women undergoing normal vaginal delivery or emergency Cesarean section.
- Administration of a single 100mg dose of diclofenac rectal suppository post-delivery.
- Assessment of postpartum pain intensity (mild, moderate, severe) at 12 and 24 hours post-administration using SPSS 16 for analysis.
Main Results:
- Perineal pain was predominantly mild in 56% of patients, moderate in 35.5%, and severe in 8.28%.
- The study included women across various age groups: 37.28% aged 20 or less, 50.3% aged 21-30, and 12.43% aged 31-40.
Conclusions:
- Diclofenac rectal suppositories represent a simple and highly effective method for reducing postpartum perineal pain.
- The findings support the use of NSAIDs as a valuable tool in managing pain after childbirth.
Related Concept Videos
01:21Drugs for Treatment of Constipation-Predominant IBS
1.1K
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
1.1K
01:17Drugs for Treatment of Diarrhea-Predominant IBS
842
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
842
01:25Assessment of the Rectum and Anus
1.6K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
1.6K
01:29Drugs for Treatment of Ulcerative Colitis in IBD
594
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
594
01:25Analgesia and Pain Management
2.7K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.7K
01:21Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
598
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
598