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A Protocol to Acquire the Degenerative Tenocyte from Humans
Published on: June 9, 2018
Rehabilitation of Tendon Problems in Patients with Diabetes Mellitus
Jonathan Rees1,2,3, Jamie E Gaida4, Karin Grävare Silbernagel5
1Department of Rheumatology, Cambridge University Hospitals, Addenbrooke's Hospital, Cambridge, UK.
Abstract:
Exercise is crucial in the management of diabetes mellitus and its associated complications. However, individuals with diabetes have a heightened risk of musculoskeletal problems, including tendon pathologies. Diabetes has a significant impact on the function of tendons due to the accumulation of advanced glycation end-products in the load-bearing collagen. In addition, tendon vascularity and healing may be reduced due to diabetes-induced changes in the peripheral vascular system, and impaired synthesis of collagen and glycosaminoglycan. The current chapter presents an evidence-based discussion of considerations for the rehabilitation of tendon problems in people with diabetes. The following conditions are discussed in detail - calcific tendinopathy, tenosynovitis, tendon rupture, and non-calcifying tendinopathy. Common diabetes-related findings are presented, along with their potential impact on tendinopathy management and suggested modifications to standard tendinopathy treatment protocols. A holistic approach should be used to optimize musculotendinous function, including a comprehensive exercise prescription addressing strength, flexibility, and aerobic fitness.
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