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Molecular Rotors for the Detection of Chemical Warfare Agent Simulants
Tae-Il Kim1, Shubhra Bikash Maity1, Jean Bouffard2
1Department of Chemistry, Kyung Hee University , 126 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.
Abstract:
The fluorogenic probe o-OH is able to detect and quantify organophosphorus nerve agent mimics in solution and in the vapor phase following immobilization on a solid substrate, making the system a suitable candidate for the field detection of chemical warfare agents. Detection is achieved by the suppression of internal rotation upon phosphorylation of a reactive phenolate, resulting in a large fluorescence "turn-on" response.
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