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[Breast saving therapy: diagnostic problems in after care].

E Walther, R Hünig, A C Almendral

    Helvetica Chirurgica Acta
    |April 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Archives of gynecology and obstetrics·2016

    Breast-conserving therapy for early-stage breast cancer can lead to post-treatment indurations. Mammography and clinical assessment show moderate agreement for suspicious findings but high agreement for benign indurations.

    Area of Science:

    • Oncology
    • Radiology
    • Pathology

    Context:

    • Breast-conserving therapy (BCT) is a standard treatment for early-stage breast cancer.
    • Post-treatment complications, such as breast induration, can mimic cancer recurrence.
    • Accurate differentiation between benign induration and tumor recurrence is crucial for patient management.

    Purpose:

    • To evaluate the diagnostic accuracy of clinical examination and mammography in distinguishing post-BCT breast indurations from tumor recurrence.
    • To assess the correlation between clinical findings, mammographic results, and histopathological confirmation of recurrence.

    Summary:

    • A study of 275 early-stage breast cancer patients treated with BCT found that 54 developed breast indurations.
    • For clinically suspicious indurations, mammography had 40% diagnostic accuracy, and microscopic confirmation of recurrence was 53%.

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  • Clinically benign indurations showed over 80% agreement with mammographic and microscopic findings, with a low rate of actual recurrence.

    • Impact:

    • Clinical assessment and mammography have limitations in definitively diagnosing recurrence when indurations are suspicious.
    • High correlation for benign indurations suggests these imaging and clinical methods are reliable in excluding recurrence.
    • Findings emphasize the need for careful evaluation and potentially further diagnostic steps for suspicious post-treatment changes.