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Updated: Mar 16, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic C-H functionalization
1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China. yhliu@sioc.ac.cn.
Abstract:
A gold-catalyzed cyclization of 1,6-diynyl dithioacetals has been developed, which provides an attractive route to diverse-substituted benzo[a]fluorene derivatives. The reaction is initiated through 1,2-sulfur migration of a propargyl dithioacetal moiety to generate a vinyl gold carbene, which is followed by carbene transfer to the remaining alkyne and aromatic substitution to furnish the fused products in generally good to high yields.
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