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Cardiovascular Testing in Asymptomatic Patients: Carotid Duplex, Cardiac Stress Testing, Screen for Peripheral
1Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 3701 Market Street, 7th Floor, Philadelphia, PA 19104, USA.
Insights
Screening for silent cardiovascular diseases like carotid stenosis, coronary artery disease, and peripheral arterial disease is not clearly beneficial. This review examines the evidence, costs, and outcomes of these screening tests.
Area of Science:
- Cardiovascular Medicine
- Preventive Cardiology
- Health Economics
Background:
- Cardiovascular disease accounts for a significant portion of US deaths.
- Managing modifiable risk factors is crucial for preventing heart disease and stroke.
- Identifying asymptomatic disease may reduce morbidity and mortality.
Purpose of the Study:
- To review the evidence for routine screening of carotid stenosis, coronary artery disease, and peripheral arterial disease.
- To analyze the costs associated with these screening tests.
- To explore the implications of positive screening results.
Main Methods:
- Literature review of existing studies on screening tests for cardiovascular conditions.
- Analysis of cost-effectiveness data for screening interventions.
- Examination of outcomes following positive screening results.
Main Results:
- Evidence for the benefit of routine screening for these conditions is currently unclear.
- Screening tests can be expensive, raising questions about cost-effectiveness.
- The implications of positive findings require careful consideration in clinical practice.
Conclusions:
- The utility of routine screening for asymptomatic carotid stenosis, coronary artery disease, and peripheral arterial disease needs further investigation.
- Cost-benefit analyses are essential when considering widespread screening programs.
- Clinical guidelines should be based on robust evidence regarding the net benefit of screening.
Abstract:
Approximately one-third of deaths in the United States are from cardiovascular disease. Managing modifiable risk factors is paramount to reducing risk of heart disease and stroke. It is logical to try to identify patients with silent disease that may predispose them to significant morbidity and mortality. Unfortunately, it is unclear if routine screening for the presence of carotid stenosis, coronary artery disease, and peripheral arterial disease is beneficial. Many of these tests are expensive. This review explores the evidence behind screening tests, costs associated with the tests, and the implications of positive screening for each of the 3 listed conditions.
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