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Updated: Mar 16, 2026
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Phantosmia and Migraine With and Without Headache
Yasmin I Jion1, Brian M Grosberg2, Randolph W Evans3
1National Neuroscience Institute, Singapore (Y.I. Jion). Yasmin_idu_jion@nni.com.sg.
Headache
|August 23, 2016
Summary
Phantosmia, a rare migraine aura, can occur before or even without headaches. These two cases highlight phantosmia as a potential, albeit uncommon, migraine symptom.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Phantosmia, the olfactory hallucination of a smell that is not present, is an uncommon neurological symptom.
- Migraine aura typically manifests as visual disturbances but can include other sensory phenomena.
Observation:
- Two patients experienced phantosmia as a symptom preceding migraine headaches.
- In both cases, phantosmia also occurred independently, without any subsequent or concurrent headache.
Findings:
- These cases represent the third and fourth documented instances of phantosmia associated with migraine aura, particularly in the absence of a headache.
- The findings suggest phantosmia can be a standalone manifestation of migraine aura.
Implications:
- This expands the known spectrum of migraine aura symptoms.
- Further research is warranted to understand the neurobiological mechanisms linking phantosmia and migraine.
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