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Related Experiment Video

Updated: Jul 4, 2025

Using Retinal Imaging to Study Dementia
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Retinal migraine.

Brian M Grosberg1, Maria Veronesi2

  • 1Hartford HealthCare Headache Center, Ayer Neuroscience Institute, West Hartford, CT, United States; Department of Neurology, University of Connecticut, Farmington, CT, United States.

Handbook of Clinical Neurology
|February 2, 2024
PubMed
Summary
This summary is machine-generated.

Retinal migraine typically causes temporary vision loss. However, this condition may also lead to permanent vision loss in nearly half of affected individuals, expanding the known spectrum of retinal migraine.

Keywords:
AuraMigraine associated with monocular visual symptomsMonocular visual disturbanceNegative visual phenomenaOcular migrainePositive visual phenomenaRetinal migraineSpreading depressionTransient monocular blindness

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Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Retinal migraine is defined by recurrent, transient monocular visual loss associated with migraine headache.
  • It predominantly affects women of child-bearing age with a history of migraine with aura.
  • Typical attacks involve partial or complete visual loss lasting under an hour.

Approach:

  • This study reviews findings related to the spectrum of retinal migraine.
  • It examines the relationship between transient visual loss and subsequent permanent visual deficits.

Key Points:

  • Current diagnostic criteria for retinal migraine mandate fully reversible visual loss.
  • Evidence suggests that irreversible visual loss can be part of the retinal migraine spectrum.
  • Nearly 50% of patients experiencing recurrent transient monocular visual loss later developed permanent monocular visual loss.

Conclusions:

  • The clinical presentation of retinal migraine may include irreversible visual loss.
  • This expands the understanding of retinal migraine, suggesting a broader spectrum of visual disturbances than previously recognized.