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Optical Coherence Tomography and Biometry in High Myopia with Tilted Disc
Nasrin Moghadas Sharif1, Nasser Shoeibi, Asieh Ehsaei
1*MSc †MD ‡PhD Refractive Errors Research Center, School of Paramedical Sciences (NMS, AE), Department of Optometry, School of Paramedical Sciences (NMS, AE), Retina Research Center (NS), and Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran (NS); and School of Optometry and Vision Science, University of Bradford, Bradford, United Kingdom (EAM).
Highly myopic eyes with tilted optic discs show greater myopia but similar biometric parameters. Optical coherence tomography (OCT) reveals differences in macular nerve fiber layer thickness, aiding in differentiating tilted optic discs.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Myopia Research
Background:
- High myopia is a significant risk factor for various ocular pathologies.
- Tilted optic discs are an anatomical variation that can be associated with refractive errors and visual field defects.
Purpose of the Study:
- To compare retinal thickness and biometric parameters in highly myopic eyes with and without tilted optic discs.
- To investigate the relationship between optic disc tilt and ocular structural characteristics.
Main Methods:
- Sixty highly myopic individuals (mean spherical equivalent refraction ≥ -6.00 D, axial length ≥ 26 mm) were examined.
- Spectral domain optical coherence tomography (OCT) and Lenstar biometry were used.
- Disc ovality (index of tilt) was assessed; a ratio ≤ 0.80 defined a tilted optic disc.
Main Results:
- No significant differences in general biometric parameters were found between groups.
- The tilted optic disc group exhibited significantly greater myopia (-8.82 ± 1.58 D vs. -7.84 ± 1.22 D).
- OCT revealed significant differences in macular nerve fiber layer thickness in nasal, inferior, and temporal quadrants, and outer temporal ring thickness.
Conclusions:
- Mean spherical equivalent refractive error is strongly correlated with optic disc tilt.
- Optical coherence tomography (OCT) is valuable for differentiating tilted optic discs from normal discs.
- Peripapillary retinal nerve fiber layer (RNFL) thickness is not significantly affected by tilted optic discs.
