Related Experiment Video

Updated: Mar 16, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

4.5K

Very Long-Term Follow-Up After Coronary Rotational Atherectomy: A Single-Center Experience

Aly Tohamy1,2, Margo Klomp1, Hein Putter3

  • 11 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.

Angiology
|August 25, 2016
PubMed

Insights

Coronary rotational atherectomy (RA) shows reasonable long-term results, particularly when combined with drug-eluting stents (DES). This study offers the longest follow-up data for RA, with 10-year major adverse cardiac events (MACE) at 57.9%.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Technology Assessment

Background:

  • Coronary rotational atherectomy (RA) is a percutaneous coronary intervention technique used for complex coronary artery disease.
  • Long-term outcomes following RA, especially in unselected patient cohorts, require further investigation.
  • The role of adjunctive stenting, particularly drug-eluting stents (DES), in modifying long-term RA outcomes is not fully elucidated.

Purpose of the Study:

  • To evaluate the very long-term clinical outcomes of patients treated with coronary rotational atherectomy (RA).
  • To compare major adverse cardiac events (MACE) in patients treated with RA plus drug-eluting stents (DES) versus those treated with RA without DES.
  • To identify factors contributing to long-term MACE after RA.

Main Methods:

  • Retrospective analysis of 143 unselected patients who underwent RA between 2000 and 2013.
  • Assessment of major adverse cardiac events (MACE), defined as target vessel revascularization (TVR), acute myocardial infarction, and all-cause mortality.
  • Comparison of outcomes between patients receiving RA with DES (n=68) and those receiving RA without DES (n=75), with a mean follow-up of 8.2 years.

Main Results:

  • The 10-year cumulative incidence of MACE for all patients was 57.9%.
  • Patients treated with RA plus DES had a significantly lower 10-year MACE rate (49.2%) compared to those treated with RA without DES (62.7%), P = .160.
  • Target vessel revascularization (TVR) was the most discriminating factor for MACE, with a 10-year incidence of 10.7% in the RA + DES group versus 29.2% in the RA without DES group (P = .016).

Conclusions:

  • Coronary rotational atherectomy (RA) demonstrates reasonable very long-term clinical results.
  • The combination of RA with drug-eluting stents (DES) appears to improve long-term outcomes, particularly by reducing target vessel revascularization (TVR).
  • This study provides the longest follow-up data to date for patients treated with RA.

Keywords:
coronary interventionlong-term follow-uprotational atherectomystent

More Related Videos

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

34.3K
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

4.4K

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
363
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
562
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
499
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
303