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Suggested Protocol for Managing Acute Suppurative Cervical Lymphadenitis in Children to Reduce Unnecessary Surgical
Minsu Kwon1, Ji-Hyun Seo2, Ki Ju Cho3
1Department of Otorhinolaryngology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea.
Insights
Antibiotics alone effectively treat pediatric acute suppurative cervical lymphadenitis (ASCL), showing no significant difference in recovery compared to surgery. This suggests avoiding unnecessary operations in stable ASCL patients.
Area of Science:
- Pediatric infectious diseases
- Surgical management of lymphadenitis
- Antibiotic therapy protocols
Background:
- Acute suppurative cervical lymphadenitis (ASCL) is common in children.
- The role of surgery in ASCL management is not well-defined.
- Need for evidence-based protocols to guide treatment decisions.
Purpose of the Study:
- To develop a management protocol for pediatric ASCL.
- To minimize unnecessary surgical interventions.
- To compare outcomes of antibiotic therapy versus surgical drainage.
Main Methods:
- Retrospective study of 75 pediatric ASCL patients.
- Group 1: Antibiotics alone (n=45).
- Group 2: Surgical intervention (n=30).
- Matched case-control analysis (20 vs. 20) for secondary outcomes.
- Primary outcome: Patient characteristics and radiologic findings.
- Secondary outcome: Treatment benefits (time to resolution, lab normalization, hospitalization duration).
Main Results:
- No significant differences in initial patient characteristics or radiologic findings between groups.
- Antibiotics alone demonstrated successful treatment outcomes comparable to surgery.
- No significant differences in symptom resolution, laboratory normalization, or hospitalization duration (P > .05).
Conclusions:
- Suppurated lymph node size/location are not absolute surgical indications in stable pediatric ASCL.
- Consider careful reevaluation and image-guided aspiration for patients not improving with antibiotics.
- Antibiotic therapy can be a primary treatment modality, reducing need for surgery.
Objectives:
The indications and benefits of surgery in the management of pediatric acute suppurative cervical lymphadenitis (ASCL) remain unclear. We aimed to design a management protocol focusing on the avoidance of unnecessary operation in pediatric ASCL patients.
Methods:
The study population consisted of 45 pediatric patients with ASCL treated with antibiotics alone and 30 surgically treated patients. The primary outcome was the determination of differences in patient characteristics and radiologic findings in the 2 groups. The secondary outcome, after matching 20 cases with 20 controls, was to determine the benefits of surgery to patients.
Results:
There were no significant differences between the 2 groups in patient characteristics and radiologic findings at initial presentation. In the matched case-control analysis, intravenous antibiotics alone yielded successful treatment outcomes when compared with surgery, with no significant differences in time to symptom resolution, normalized laboratory test results, and duration of hospitalization (all P > .05).
Conclusions:
The size and location of suppurated lymph nodes are not absolute determinants for surgical drainage in the stable pediatric ASCL patients. If patients show no clinical improvements despite appropriate second- and third-line antibiotics, patients should be carefully reevaluated and image-guided aspiration considered.
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