Related Experiment Video
Updated: Mar 16, 2026

Generation of Zerovalent Metal Core Nanoparticles Using n-2-aminoethyl-3-aminosilanetriol
Published on: February 11, 2016
Metal-based ethanolamine-derived compounds: a note on their synthesis, characterization and bioactivity
Muhammad Amjad1, Sajjad H Sumrra2, Muhammad Safwan Akram3
1a Institute of Chemical Sciences, Bahauddin Zakariya University , Multan , Pakistan.
Abstract:
Metal-based ethanolamines, (L1)-(L4) coordinated with Co(II), Cu(II), Ni(II) and Zn(II) metals in 1:2 (metal:ligand) molar ratio to produce new compounds have been reported. These compounds were screened for their bactericidal/fungicidal activity against a number of bacterial (Escherichia coli, Shigella flexneri, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus and Bacillus subtilis) and fungal strains (Trichophyton longifusus, Candida albicans, Aspergillus flavus, Microsporum canis, Fusarium solani and Candida glabrata) alongside against a shrimp species known as Artemia salina. The screening results indicated that metal complexes have significantly higher activity than uncomplexed ligands against one or more bacterial/fungal species due to chelation. The ligand (L4) displayed good bacterial and fungal activity as compared to other ligands. The antibacterial results revealed that the Zn(II) complex (16) of (L4) was found to be the most active complex and Co(II) complex (14) of the same ligand (L4), demonstrated the highest antifungal activity.
Related Concept Videos
Aldehydes and Ketones with Amines: Imine and Enamine Formation Overview
Synthesis of α-Substituted Carbonyl Compounds: The Stork Enamine Reaction
Aldehydes and Ketones with Amines: Enamine Formation Mechanism
Properties of Organometallic Compounds
Complexation Equilibria: The Chelate Effect
EDTA: Auxiliary Complexing Reagents

