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[Teriparatide:benefit and safety for bone disease in CKD patients undergoing hemodialysis]
Suguru Yamamoto1, Isei Ei2, Ichiei Narita3
1Blood Purification Center, Niigata University Medical and Dental Hospital, Niigata, Japan.
Abstract:
Teriparatide, 1-34 parathyroid hormone, is one of effective treatments for osteoporosis. Teriparatide shows an anabolic effect for bone formation, as a result, increases bone mineral density as well as prevention of fractures in the general population. On the other hand, there are a few report about the effect of teriparatide on increase of bone mineral density in maintenance hemodialysis patients. In addition to CKD-MBD, osteoporosis is also an important pathological change in ESRD patients, therefore its safety and efficacy should be discussed in more detail.
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