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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[Prolonged response with paclitaxel after immunotherapy by pembrolizumab in lung cancer]
E Zapata1, B Mennecier1, C Leduc1
1Service de pneumologie, nouvel hôpital Civil, hôpitaux universitaires de Strasbourg, Strasbourg, France.
Introduction:
Pembrolizumab, a humanized monoclonal antibody IgG4 anti-PD-1, having offered promising results in patients suffering from non-small cell lung cancer metastatic and heavily pretreated.
Observation:
We report here the case of an unexpected good response after pembrolizumab failure obtained with paclitaxel in a 68-year-old patient with stage IV lung adenocarcinoma. Moreover, the response duration with paclitaxel was more than fourteen months.
Conclusion:
Our case suggests a mutual potentiation of chemotherapy and immunotherapy, and raises the issue of the treatment sequence to favor.
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